This new test greatly expands the parameters of gluten sensitivity testing, catching those who may have previously tested negative because they don’t react to the alpha gliadin. A ‘false negative’ occurs when the test results says a condition is not present, when in reality there is a problem.  Many forms of standard testing for celiac disease or gluten sensitivity do not include the right markers or enough of the right markers.  Using Cyrex Array 3 allows for more accurate results with fewer ‘false negatives’.

The test is recommended for individuals who have:

• Non-responsive intestinal complaints including irritable bowel syndrome and colitis
• Chronic, multiple system complaints, including chronic fatigue syndrome and fibromyalgia
• Depression, any type of auto-immunity, neurological conditions including ADHD and Parkinson’s
• Chronic anemia  and skin conditions such as rosacea, eczema and psoriasis and canker sores
• Headaches and migraines, and hormonal problems including infertility and PMS
• other illusive complaints and conditions for which no answers are given

Opioid testing

Array 3 screens for antibodies to the opioids produced from wheat called Gluteomorphins and Prodynorphins.  Gluten can have a drug-like opiate effect on an individual.  Antibodies to gluteomorphin and prodynorphin can indicate that gluten is affecting your brain.  Some people have enzymes in their digestive tract that break gluten down into opioids that act like heroin or morphine.  Embarking on a gluten-free diet can cause terrible withdrawal symptoms in these people.  One practitioner tells of a patient whose withdrawal symptoms were so severe she went to the emergency room.
Another problem with opioids is they disrupt brain function by attaching to receptor sites normally meant for neurotransmitters.  Neurotransmitters are brain chemicals that help dictate our personality, moods, behavior, bodily function, and more.
This opioid effect on neurotransmitter receptors explains why gluten plays a role in so many cases of ADD/ADHD, autism, or behavioral problems in children; or brain fog, depression, anxiety, schizophrenia, anorexia and migraines in adults.  When one mother put her autistic son on a gluten-free diet, he began eating the binding out of books as he was so desperate for his gluten-opioid “fix.”

Lectins

Array 3 also includes testing for antibodies to the wheat lectin Wheat Germ Agglutinin (WGA).  WGAs are lectins or carbohydrate-binding proteins with a capacity to bind to many cells and tissue antigens.  Lectins can bind to cells involved in the immune system and induce toxic damage, inflammation and autoimmunity.

Enzymes

Array 3 includes testing for antibodies to enzymes:  Tissue Transglutaminases -2, -3 and -6 and Gliadin-Tranglutaminase Complex.  Transglutaminases are a family of enzymes that form protein polymers, like scaffolding, which are vital in the formation of barriers and stable structures such as gut tissue.  Antibodies may appear in serum before the clinical onset of symptoms.

Gliadin-Transglutaminase IgG can assist with diagnosing Celiac Disease.

Tissue Transglutaminase-2 (tTG2) is commonly recognized for being an effective diagnostic test for celiac disease.  Transglutaminase is an enzyme in the digestive tract targeted in an autoimmune attack triggered by gluten. tTG2 antibodies indicate gluten is attacking gut tissue through an autoimmune attack.

Tissue Transglutaminase-3 (tTG3) is express mainly in the epidermis (skin disorders) and to a lesser extent in the placenta and the brain.

Tissue Transglutaminase-6 (tTG6) is expressed in neural tissue.  tTG6 may be involved in the pathogenesis of gluten reactivity-related neurological dysfunction.
Price: $425.00

Cyrex Array 4: Gluten-Associated Sensitivity and Cross-Reactive Foods

In cross-reactivity, the body may mistake another food for gluten and react accordingly.  Array 4 tests for 24 different foods that may be causing cross-reactivity or are newly introduced to the diet or over-consumed favorites.
One of the most frustrating scenarios for both the practitioner and the patient is when a gluten-free diet fails to have any effect on a person who seems so clearly gluten sensitive. Newer research shows this may be due to cross-reactivity.  In cross-reactivity, the body mistakes another food for gluten and reacts accordingly.  Array 4 tests for 24 different foods that may be causing cross-reactivity or are newly introduced to the diet or over-consumed favorites.   Array #4 Tests for the following Foods:

People typically shrug off the possibility of gluten sensitivity by saying, “I don’t have any digestive problems.”  Little do they know that gluten produces digestive symptoms in only a minority of people (1 out of 8).  For the majority, gluten can damage the brain, the heart, the skin, the respiratory tract or the joints.

Cyrex Array 5 can be useful for Patients who:

• Have been diagnosed with an autoimmune disorder, as they commonly develop additional autoimmune conditions
• With chronic increased intestinal permeability, which is the gateway for environmentally-induced autoimmune disorders
• Chronic increased intestinal  permeability (Array #2), which is the gateway for  environmentally-induced autoimmune disorders

The Cyrex Array 5 is an economical and effective way to assess possible tissue damage to multiple organs of the body and will help you assess predictive antibodies.  Elevated numbers of antibodies, known as Predictive Antibodies, are measurable up to ten years before the clinical onset of the disease. Identification of pathogenesis at this stage allows for the possible arrest or even reversal of disease progression.

 Array 5 – Systemic Autoimmune Reactivity Screen™ looks at multiple tissues commonly targeted by auto-antibodies, including heart, thyroid, joint, gut, brain, liver, thyroid, ovaries, bone and more.     Price: $675.00